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The SELECT cardiovascular outcomes trial showed that semaglutide 2.4 mg significantly reduced major adverse cardiovascular events (heart attack, stroke, and cardiovascular death) in patients with established cardiovascular disease and overweight or obesity, even without type 2 diabetes

However, long-term dietary restriction is challenging to implement broadly in the elderly population, as it may lead to malnutrition and muscle wasting

OHearn, A

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And the way to be able to do that is a couple of things