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Injections can cause minor effects such as irritation or itching at the injection site, and the consumer fact sheet is a good plain-language reference on what B12 does and does not do

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However, it is better to administer it at night as a precaution to avoid differing views. Majm al-Fatw: 15/257 Shaykh Ibn Uthaymn ( ): There is no harm in injections in the vein, muscle, or thigh, and they do not break the fast