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47 A randomized placebo-controlled trial with 101 menopausal participants found a combination of 520 mg black cohosh, 400 mg chaste tree, 100 mg soy isoflavones, and 500 mg evening primrose oil, taken once daily for 12 weeks, improved hot flashes and sweating, sleep problems, mood, and irritability, as well as levels of C-reactive protein (CRP) (a marker of inflammation), LDL-cholesterol, and triglycerides

Peptides discussed are intended for research use only and are not approved for human use or consumption

Adiponectin stimulates production of nitric oxide in vascular endothelial cells

It enhances fatty acid metabolism in cardiac tissue, which relies heavily on fat for energy