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1 Introduction Rotator cuff tears (RCTs) are a leading cause of shoulder pain and dysfunction, accounting for nearly 50% of shoulder-related disorders (Paolucci et al., 2023)

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Peer review Peer review information Nature Reviews Molecular Cell Biology thanks Michael Murphy, Navdeep Chandel, Isaac Harris and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Xia, M., et al., Reversal of obesity-induced hypertriglyceridemia by (R)--lipoic acid in ZDF (fa/fa) rats