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Abstract The objective of this study was to compare the effectiveness of subcutaneous (SC) and sublingual (SL) formulations of apomorphine for the treatment of motor fluctuations in Parkinsons disease using a pharmacokinetics (PK)/pharmacodynamics (PD) modeling approach

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However, these resulting effects of NRF2 induction via CDDO treatment were to a dramatically lower degree compared to the effects of NRF2 induction upon GSH depletion in Gclc L-KO mice (Figs