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High vitamin B12 levels may also be present in people with conditions such as liver disease and certain cancers
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[2] It is important to note that whilst fatigue and general malaise may improve relatively quickly, complete symptom resolution requires adequate time for the body to replenish B12 stores and repair affected tissues
These findings do not establish a direct cause-and-effect relationship, but they suggest that long-term high-dose supplementation may not be necessary for individuals with adequate B12 status
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