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Pain or Irritation at the Injection Site One of the most common side effects is mild discomfort or irritation at the site of the injection

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Other signs of injury include: [1] [6] Edema, or swelling in the soft tissue structures around the joint Effusion, or swelling within the joint capsule Reluctance to bear weight on the affected limb Reduced range of motion in the fetlock Pain on palpation Lameness, such as a shortened stride in the affected limb A dropping of one or both fetlocks that is lower than normal Diagnosis To diagnose fetlock injury in your horse, your veterinarian will perform a musculoskeletal exam

PMID 2137911 Subcutaneous injection-site pharmacokinetics FDA review

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