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Patients received once-daily orforglipron (6, 12, or 36 mg) or placebo for 72 weeks

Symptoms can include: decreased urination swelling in legs and ankles confusion fatigue Increased low-density lipoprotein cholesterol levels Other serious side effects, explained in more detail below in Side effect details, include: Ketoacidosis (buildup of ketones in the body, causing your blood to be too acidic) Serious urinary tract infections (including urosepsis and pyelonephritis) Fourniers gangrene (severe infection near the genitals) Genital yeast infection Serious allergic reactions Side effect details You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it

Can help to prevent inflammation in skin An emollient that is naturally found in skin A type of lipid that is naturally present in skin