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& Vasi, F

Collectively, astrocytes contribute to CNS homeostasis through their roles in releasing neurotrophic factors, phagocytosing injured neurons, and maintaining a supportive environment necessary for optimal neural function

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Therefore, we collected EVs from dimethyl sulfoxide (DMSO), estradiol, and progesterone-treated BUTE-CM (6 pellets per biological replicate) and analyzed their metabolic content by non-targeted metabolomics