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The effluent was ionized via ion electrospray in negative mode on a TSQ Quantiva triple-quadrupole mass spectrometry with the following instrument settings: ion spray voltage 2500 V, sheath gas 28, ion transfer tube temperature 325, aux gas 8, and FWHM of 0.7 for both Q1/Q3 resolution

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Fang et al, 2019

Physiologically, SMCT1 can transport lactate and ketone bodies into neurons and also functions as a tumor suppressor in the brain, but the importance of this transporter in normal physiologic conditions is unknown ( Lactate Transporter-Dependent Glial Metabolism Supports Peripheral Nerve Integrity and Function Integrity and function of the PNS depends upon uninterrupted energy supply

In PRM quantification, two fragments were monitored by Quanbrowser for cortisol (363.2166) and D4 cortisol (367.2147)