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Description

Astrocyte-specific overexpression of insulin-like growth factor-I promotes brain overgrowth and glial fibrillary acidic protein expression

Improper storage is the most common reason for degradation

Kherkher Garcia

This hypersensitivity for GH further pushes up the already elevated IGF-1 production, while on top of that IGF-1 actions are also increased because of the hyperinsulinemia-induced reduction in IGFBP-1 [35]