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Documentation of metabolic dysfunction (insulin resistance, prediabetes, lipid abnormalities) improves approval odds significantly

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In the same trial, they also tested DAS (0, 223, 429, or 860 ppb) and found a similar dose relationship

Furthermore, ROS can be generated from exposure to other external sources such as cigarette smoke, pollutants, chemicals and environmental toxins

All of them were demonstrated to decrease IR at quite high dosages (12, 30, 31), also in PCOS patients undergoing IVF programs (32)