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GLP-1 receptor agonists like semaglutide are peptide drugs with strong randomized trial outcomes and clear FDA-approved indications: type 2 diabetes, chronic weight management, and since March 2024, cardiovascular risk reduction in adults with established heart disease who are overweight or obese

Annual Review of Biophysics, 40, 169-186

K., Plutzky, J., van Beek, A

These cases may be treated with brisement, in which the affected tendon is injected with a small amount of fluid, either sterile saline or lidocaine to break up scar tissue (adhesions) in the tendon