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The primary objective was to determine whether dapagliflozin 10 mg reduces the incidence of the composite endpoint of 50% sustained decline in eGFR, progression to end-stage kidney disease (ESKD) (defined as sustained eGFR 40% and evidence of structural heart disease to determine whether dapagliflozin reduces the risk of cardiovascular death, hospitalization for heart failure or urgent heart failure visits

Cancer Cell 21 , 3651 (2012)

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