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Our results have revealed both the activation of AMPK and S6K in the VMH and LH in response to changes in glucose concentration or nutritional state, and that GLP-1/exendin-4 acts by counteracting the activation/inactivation of these kinases and contributing to the balance of proper AMPK and S6K activation

GI Symptoms: Nausea, bloating, or early fullness are common

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Summary: Lightheadedness on Mounjaro (tirzepatide) commonly results from dehydration, blood pressure changes, or low blood sugar, particularly during treatment initiation or when combined with other diabetes medications

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