Preclinical findings may suggest mechanisms worth studying, but limited human evidence cannot establish broad clinical effectiveness, optimal dosing, long-term safety, or superiority over standard care
Caveolae, a portion of lipid rafts, form through the integration of the protein CAV-1, which are upheld by the cytoskeleton
Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling
The real therapeutic opportunity may lie in viewing neuronglia interactions as druggable units, rather than treating these cell types in isolation
Nese Atabey, Dokuz Eylul University, Turkey Updates Copyright 2020 Wang, Rao, Lou, Li, Liu, Li, Cui, Ren and Yu