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Overall, there is substantial preclinical evidence and mounting retrospective and prospective RCT evidence that GLP-1RAs could be effective for reducing alcohol consumption

Its medical burden includes multiple comorbidities, such as type 2 diabetes, hypertension, dyslipidemia, stroke, coronary heart disease, and various cancers

Arnott C, Neuen BL, Heerspink HJL, et al

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Another possible reason for mood changes is sleep disruption