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Impairment of Fertility In rat fertility studies with oral gavage doses of 5, 15, 50 mg/kg/day, males were treated for 9 weeks prior to and throughout mating and females were treated 2 weeks prior to mating and throughout mating until gestation day 7
These disruptions are expected to drive growth and immense changes in the GLP-1 agonists market
It is thought that high-risk variants cause APOL1-mediated kidney disease in a way that is very similar to how it causes cytotoxicity in laboratory animals
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