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(D) CHX-treated W8 cells overexpressing Flag-CRIP1 WT or R26/68K were analyzed by Western blot for Flag expression in NCI-H446 cells

A better understanding of these adaptive mechanisms of gastric mucosa after RYGB and VSG and their exploitation will help in the development of new approaches to bariatric surgeries and possibly allow to replace them with less invasive and gastric-targeted endocrine therapies for the treatment of obesity-related diabetes

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FHA domains typically consist of eleven -strands (1- 11) interspaced with six loop regions (L1-L6), and recognize a single P-Thr via residues on apical surfaces of the loops 44,45