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Given that sensory or gastrointestinal adverse effects, such as dysgeusia and persistent nausea, can impair nutritional intake and lead to early treatment discontinuation (particularly in vulnerable populations) future research must incorporate rigorous sensory testing, larger and more diverse cohorts, and adherence-related outcomes to clarify how incretin therapies influence taste perception and long-term eating behavior (153, 157, 161)

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doi: 10.1016/j.pnpbp.2020.109868 3 CruzBFde Campos-CarliSMde OliveiraAMde BritoCBGarciaZMdo Nascimento ArifaRDet al

89,90,91,92,93 These cytokines play a central role in orchestrating the inflammatory response by recruiting additional immune cells and amplifying the proinflammatory cascade

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