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strict eligibility: patients must have experienced a cardiovascular event such as a heart attack, stroke, or symptomatic peripheral arterial disease

The researchers found that the risk for a primary outcome event (major kidney disease events, a composite of the onset of kidney failure, at least a 50 percent reduction in the estimated glomerular filtration rate from baseline, or death from kidney-related or cardiovascular causes) was significantly lower in the semaglutide group (331 versus 410 first events

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References Wang JY, Wang QW, Yang XY, et al

Its active ingredient, Semaglutide, reduces appetite, slows digestion, and improves insulin response when blood sugar rises