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It is possible that weight loss might not have been so good if we had simultaneously achieved a significant HbA1c reduction, and it is known that intensification of insulin therapy to attain good control is associated with weight gain
While glycemic control is not traditionally considered a direct cardiovascular risk factor, it is pivotal in mitigating cardiovascular risk in T2D patients
Cardiovascular risk groups and mortality in an urban Swedish male population: the Malm preventive project
However, Contrave weight loss results may be sufficient for many patients and offers advantages in cost and administration
Thymoquinone (35), a volatile oil component, reduced both arterial BP and HR, probably through central action in the medulla oblongata, involving activation of 5-HT and muscarinic mechanisms (426)
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