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In addition, loperamide was found to reduce TNF- levels and induce the production of antimicrobial peptides, such as bactericidal/permeability increasing protein and LL37, enhancing hosts ability to fight against M.tb infections while protecting tissues from excessive inflammatory damage [13]

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(3) Gut microbiota modulation Phospholipids in fish increase gut Akkermansia muciniphila abundance, promoting SCFA production

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