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Food and Drug Administration expanded Wegovys approved use after Novo Nordisk announced that the drug cut the risk of serious heart events by 20% in a clinical trial

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Understanding these distinctions prevents unrealistic expectations while recognizing legitimate therapeutic potential

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The primary reasons for exclusion were withdrawal from follow-up at the participants discretion, treatment discontinuation due to nausea, drug supply issues, cholangiocarcinoma, pancreatitis, and treatment cessation at a non-participating institution ( Figure 1 )