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Supplementation in high doses (over 1000 mg) relatively shortly before training appears to be advisable, as circulating L-carnitine - in contrast to muscle carnitine - presumably has a vascular-protective effect against oxidative damage in the microvascular area
Some promising approaches include the following: - Garlic-derived allicin: reduces TMAO in murine models (C57BL/6 mice), suggesting anti-atherosclerotic potential ( - TMA lyase inhibitors: synthetic compounds (e.g., fluoromethylcholine, FMC) that irreversibly inhibit CutC/D ( - Probiotics: specific strains can lower TMAO levels ( 1.5 Experimental approach Here, we report the results of an alternative approach based on the use of postbioticspreparations of inanimate microorganisms and/or their components, which confer health benefits to the hostas inhibitors of intestinal TMA lyase ( Lactobacillus paracasei LMG-S-26420 ferment for 72 h under anaerobic conditions in the presence of a freeze-dried botanical hydroalcoholic extract of garlic ( Allium sativum )
Raina N, Rani R, Thakur VK, Gupta M
42 PerbandtM.BurmeisterC.WalterR
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