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Before AHK-Cu can move from the lab to medical practice, researchers need clearer data on its metabolism, safety, and possible off-target interactions

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Abstract Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even though both processes are involved in liver detoxification