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Targeted therapies and clinical research of AA metabolism (tentative) In the above modules, we introduced the mechanisms of amino acids, related metabolic enzymes, and metabolites related to the occurrence and development of diseases

To address the limitations of GLP-1 analogs, ongoing preclinical and clinical studies are evaluating the combined use of MSTN inhibitors and GLP-1 agonists

LigandScout provided a pharmacophore fit score for each screened molecule

The mechanisms of action include: Enhancement of glucose-dependent insulin secretion Suppression of glucagon secretion Delay in gastric emptying Increased satiety and appetite suppression These effects collectively lead to improved glycemic control and significant weight reduction