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In the published Phase 1/2 trial, CJC-1295 with DAC showed no serious adverse events at doses up to 60 mcg/kg

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Diabetes and obesity, both of which are associated with the secretion of pro-inflammatory adipokines and the reduced availability of nitric oxide, may lead to the occurrence of HFpEF in young individuals due to myocardial remodeling and fibrosis [7, 34]

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