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Hair pigmentation is regulated by melanogenesis within the follicle and modulated by various factors, including melanocyte-stimulating hormone (MSH), adrenocorticotropic hormone (ACTH), endothelin-1, prostaglandins, leukotrienes, fibroblast growth factors, nitric oxide, catecholamines, as well as essential vitamins and minerals

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4 In the modern era, obesity is typically defined as a body mass index (BMI) 30 kg/m 2 , while a BMI value of 2529.9 kg/m 2 is classified as overweight

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