This prescription requirement ensures that the medication is used safely and effectively while minimizing potential risks or complications
The medication's effects on gastric emptying, weight loss velocity, and metabolic changes all have potential implications for gallstone formation, making this an important clinical consideration for prescribers and patients alike
Currently, neither drug is widely covered by South African medical aids for the treatment of obesity, but this could change as demand increases
Immediate medical attention is required if taste changes are accompanied by: Severe, persistent vomiting preventing adequate fluid intake Signs of dehydration (dark urine, dizziness, decreased urination) Severe abdominal pain, particularly if persistent or worsening Symptoms of pancreatitis (severe upper abdominal pain radiating to the back, nausea, vomiting) Right upper quadrant pain, fever, or yellowing of skin/eyes (possible gallbladder disease) Symptoms of hypoglycemia (if also taking insulin or sulfonylureas): shakiness, sweating, confusion, irritability These symptoms may indicate serious adverse effects requiring urgent evaluation, including pancreatitis, gallbladder disease, gastroparesis, or severe dehydration
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