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The highest volume of distribution was observed for diosgenin (2.5 ml/kg) followed by charantin (1.4 ml/kg) and least was observed for hydroxychalcone (0.27 ml/kg), indicating high protein binding of hydroxychalcone and ultimately low t 1/2 and lower clearance of drug from the body

The researchers initially attributed the drugs success in mouse studies to its ability to reduce or eliminate androgen receptors in the prostate cancer cells

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Vitamin B12 can exist as cyanocobalamin, methylcobalamin, adenosylcobalamin and hydroxycobalamin

Int J Pharm Drug Anal