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Discoloration of skin and urine after treatment with hydroxocobalamin for cyanide poisoning
It contains various vitamins that help in proper brain function, boosting body energy levels and are important for proper functioning of the nervous system
This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes
The NHS provides resources on maintaining adequate B12 intake for those following plant-based diets, emphasising the importance of fortified foods such as breakfast cereals, plant-based milk alternatives, and yeast extract products commonly available in the UK
It is a useful reminder to consider vitamin B12 deficiency in people taking metformin who have megaloblastic anaemia, neuropathy or other symptoms suggestive of deficiency
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