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(2019) who investigated the risk of developing IBD in patients on DPP-IV inhibitor therapy point out the need for further research

Inhibitors of DPP-4 showed only minimal pharmacokinetic changes in patients with varying degrees of hepatic impairment.70 Among agonists of GLP-1 receptors, only liraglutide has been studied in patients with CLD.72 No increase in liver enzymes was observed with this drug alone or combined with other agents

Epidemiological studies have reported that women get sick and die more often from CVD compared to men

Additionally, K2 plays a role in supporting vascular health, which is important for maintaining healthy circulation, including to the brain