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In the USA and EU, AOD-9604 never achieved regulatory approval

Only qualified professionals should handle this material in appropriate laboratory environments and in compliance with all applicable laws and regulations

Its not uncommon in medicine to encounter situations where a treatment, especially one addressing a longstanding deficiency, might initially seem to exacerbate symptoms

AOD-9604 doesnt have FDA approval for weight loss, but it does have GRAS status to be used as a supplement in certain instances