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B12 is involved in fatty acid metabolism that builds an insulating lipid-rich layer surrounding a neurons axon (the myelin sheath), which speeds up nerve signals and enhances learning and logical thinking processes

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[4] The folic acid injection products may contain aluminum which may reach toxic concentrations with prolonged administration in patients with renal failure, renal disease, renal impairment, or in premature neonates with immature kidneys

Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79