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From a pharmacological safety perspective, the adverse effect profile of retatrutide based on Phase 1 and Phase 2 clinical trial data (including the NEJM 2023 Phase 2 trial) includes: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (the most commonly reported side effects in trial participants) Injection site reactions: Redness, swelling, or discomfort at the injection site Cardiovascular effects: Increases in heart rate have been observed in trial participants [21] [22] Hypoglycaemia: Particularly relevant in individuals with diabetes or those taking insulin, sulfonylureas, or other glucose-lowering agents Potential thyroid effects: GLP-1 receptor agonists have been associated with thyroid C-cell changes in rodent studies

In order to compensate for the anemia, the liver and spleen increase in size and the bone marrow in all the bones including the skull and face bones and long bones tries to make blood

doi: 10.1093/nar/gki248

Collagen supplementation: Oral collagen peptides (10-15g daily) provide specific amino acids (glycine, proline, hydroxyproline) enriched in connective tissue

MIC B12 injections are recommended for adults who are seeking to increase their metabolism, burn fat more quickly, and are willing to commit to a healthy lifestyle