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Concentrations are highest in youth (around 200 ng/mL in young adults) and decline with age to approximately 80 ng/mL by age 60

The following script was used for running the structural prediction process: colabfold_batch --model-type AlphaFold2--num-recycle 48 --amber --use-gpu-relax) 75 using the amino acid sequence of NAPstar3 as input (Supplementary List 1)

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With a better molecular understanding of such specific mechanisms, adjunctive therapies can be developed for a combination treatment strategy, as is the standard approach for many other diseases