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A erva-mate possui compostos que retardam significativamente o esvaziamento gstrico, imitando o exato mecanismo fisiolgico dos medicamentos agonistas do GLP-1

Furthermore, recent studies have demonstrated that GLP-1RAs may exert their anorexigenic effects not only by acting on ARC POMC neurons but also in other brain regions, such as the dorsomedial hypothalamus (DMH) and the dorsal vagal complex in the hindbrain [8, 9]

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When they are in a healthy range they are usually between 200 and 300 ng/ml