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Homozygous PRC2 inactivation induces complete loss of trimethylation at lysine 27 of histone 3 (H3K27me3)

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This effect substantially weakened in the post-S1 blood sample (Treatment Time S1 meal type S2 meal type interaction in the main model: t 50.0 = 2.61, p = 0.012), though BGL was still significantly lower under Ex compared to Vehicle control treatment (post-S1, Treatment: F 1,4.1 = 24.23, p = 0.0073)

Immunity 15:303311 Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE (1992) Rag-1-deficient mice have no mature lymphocytes-B and lymphocytes-T