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Specifically, BDNF was necessary for differentiation but not the proliferation of newborn neurons, as the only difference between BDNF knockdown and controls was the number of cells expressing both proliferation marker (BrdU) and immature neuronal marker (DCX), whereas the total number of proliferating cells, either 24 h (Figure 5b) or 7 days (Figure 5c) after BrdU injections, was unchanged

The intestinal epithelial barrier: a therapeutic target

For neuropathy applications, some researchers consider injection sites near affected nerve territories

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The 2 mL option (5 mg/mL) keeps volumes small, which means less discomfort at the injection site and more precise measurements