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The gut microbiota produces an array of bioactive metabolites, such as short-chain fatty acids (SCFAs), neurotransmitter precursors, and uremic toxins, that mediate communication between the gut, brain, and kidneys (Lin et al., 2025)

589 Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2 (Nrf2), critical for regulating anti-oxidative stress, represents a PPI targetable by covalent inhibitors

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ITI forms collaboration with EpiVax & PharmaJet to develop novel vaccine candidate against COVID-19 using its investigational UNITE platform