Bischoff-Ferrari HA, Gngler S, Wieczorek M, Belsky DW, Ryan J, Kressig RW, Sthelin HB, Theiler R, Dawson-Hughes B, Rizzoli R, Vellas B, Rouch L, Guyonnet S, Egli A, Orav EJ, Willett W, Horvath S (2025) Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
discovered that sweet BV may impact fluctuations in heart rate, although nothing is known about its effect on CVDs (Yook et al., 2008)
IM injection: one ampoule once a day
accidental freezing), which may produce visible particles
Verdict: Limited evidence the available human safety data consists of very small pilot studies, no long-term follow-up, unresolved FDA-documented concerns, and at least one theoretical risk that has never been formally evaluated in humans [4][10][1517]