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Acetyl L-carnitine is distinguished by its particular stability

J Biol Chem 269(10):73427348 Pushpa-Rekha TR, Burdsall AL, Oleksa LM, Chisolm GM, Driscoll DM (1995) Rat phospholipid-hydroperoxide glutathione peroxidase: cDNA cloning and identification of multiple transcription and translation start sites

Pharmacokinetics: Data indicate a linear pharmacokinetic profile with a short half-life ( 1000mcg/day) have been anecdotally associated with increased chances of headaches, fatigue, or water retention, and may lead to diminishing returns, suggesting a bell-shaped dose-response curve

Figueroa J, Ortega N, Almeida L, Blanco C, Castillo R

Part of the decrease was dependent on the presence of the co-factors NADP and glucose-6-phosphate