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Genome editing can be incorporated into this process to correct genetic defects or engineer immune-evasive properties (e.g., reduced HLA expression) prior to transplantation

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The use of a methyl group is optimum in that it is small enough to not influence the overall activity of the molecule, while the rationale behind the location of the modification is to protect the most common degradation location of the peptides, i.e., the peptide bond

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Low likelihood that LP will be needed: use unfractionated heparin (5000 IU SQ qhr)