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The administration of GLP-1RA or exendin-4 to rats fed a high-fat diet resulted in an increase in the OPG/RANKL ratio and a reduction in the degree of bone loss

Common symptoms of gastroparesis include: Persistent nausea and vomiting, particularly of undigested food Early satiety (feeling full after eating only small amounts) Abdominal bloating and discomfort Upper abdominal pain Heartburn or gastro-oesophageal reflux Poor appetite and unintentional weight loss Blood glucose fluctuations in people with diabetes The condition occurs when the vagus nerve , which controls stomach muscle contractions, becomes damaged or stops functioning properly

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A study published Wednesday in JAMA Cardiology found semaglutide the ingredient in Wegovy and the diabetes drug Ozempic could substantially reduce heart attacks and strokes among U.S

In addition to lowering blood sugar, semaglutide products have been shown to help with weight loss, heart failure and potentially curbing addictive behaviors