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Science 375:9941000

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Role of gut-liver axis and glucagon-like peptide-1 receptor agonists in the treatment of metabolic dysfunction-associated fatty liver disease

Satellite Cell Activation and Sequential IGF-1 Isoform Switching The MGF hypothesis proposes that MGF is first expressed to activate quiescent satellite cells, driving their proliferation while inhibiting premature differentiation before declining to allow IGF-1Ea-mediated differentiation and myotube formation

Hepatic Fat Reduction Moderate Research Exploratory analyses from clinical trials have demonstrated significant reductions in hepatic fat content with mazdutide treatment