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Compared with the prior art, the invention has the following advantages: (1) The sequence of the coupling reaction is controlled, namely a main peptide chain is coupled with a side chain with a tertiary butyl protection on a carboxyl, then coupled with Boc-His (Trt) -Aib-OH dipeptide, and finally two protecting groups of Boc and t-Bu are simultaneously removed by a one-step method, so that the semaglutide with the purity of more than or equal to 97 percent can be obtained by only 3 steps in the whole process

Precision-cut liver slices: a tool to model the liver ex vivo

This medication can be beneficial for obese individuals who have difficulty losing weight with diet and exercise alone

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Plasma donation can be done more frequently than whole blood donation because a portion of the blood is returned to the body