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Description

Mechanistically, -Syn oligomers interact with mitochondrial respiratory chain complex I, impairing its function, leading to mitochondrial membrane potential depolarization, and promoting the release of proapoptotic factors into the cytoplasm

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This dual mechanism approach allows researchers to investigate complex cell migration phenomena in controlled experimental conditions

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Figure 1, Panel A and Figure 1, Panel B show the steady state for a male and a female, respectively

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