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In recent months, the companies have been on the receiving end of hundreds of patient lawsuits claiming that the drugs have resulted in excessive gastrointestinal symptomssometimes even necessitating surgical interventions

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35,43 Meta-analyses evaluating percutaneously placed interspinous spacer devices found that although there may be some benefit in patients without spondylolisthesis who have extension-based neurogenic claudication, there are high rates of complications and reoperation

Again, it is important to make sure that an individual presents with hypermobile Ehlers-Danlos syndrome and not one of the other subtypes

Ask About Basic Lab Work If shedding is noticeable, it is often worth discussing a basic set of labs to rule out common contributors, rather than guessing