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Symptoms of hypothyroidism may include 5 10 11 12 13 14: Tiredness Constipation Dry skin Cold intolerance Weight gain Hoarseness Mood changes Muscle pain The top two causes of overt hypothyroidism are a lack of dietary iodine (which is now rare in the U.S.) and Hashimotos thyroiditis 5

At the beginning of this study there were no reported transcript sequences for these genes and some of the genomic sequences were incomplete

This work was supported by the Lundbeck Foundation (fellowship R238-2016-2859), the BioInnovation Institute (grant number NNF20OC0063538) and the Novo Nordisk Foundation (grant numbers NNF17OC0026114 and NNF22OC0073778)

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